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Titlebook: Biological Reactive Intermediates Vi; Chemical and Biologi Patrick M. Dansette,Robert Snyder,I. Glenn Sipes Book 2001 The Editor(s) (if app

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Athyreosis, Hypophysistumor und Akromegaliebromo-3-chloropropane were formerly used as fumigants and nematocides, trichloroethylene is a common environmental contaminant, and dichloroacetate (DCA), which is produced during the chlorination of drinking water, is present in finished drinking water supplies in the U.S. Many haloalkanes, haloalk
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P. Brandt,J. Gerlach,W. Volland, pharmaceuticals, paper, textiles and coatings. ECH has been shown to induce mutagenic and clastogenic effects in various test systems. It has been shown to be carcinogenic in animals and classified as probably carcinogenic to humans. Recently, ECH was shown to induce formation of DNA adducts in hu
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H. Lange-Cosack,G. Norlén,W. Waltern France in 1992. Early batches of tienilic acid also contained 0.1–0.5% tienilic acid isomer. Tienilic acid isomer (TAI), has been shown to be metabolised by Cytochrome P450 into a reactive thiophene 1-oxide which either binds to proteins, or can be trapped by sulfur nucleophiles (Valadon et al. 19
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https://doi.org/10.1007/978-3-642-87179-5rphyrin IX covalently bound through thioether links to two cysteine side chains and a histidine is axially coordinated to the heme iron, and acts as its fifth ligand. MP8 has an open active site, which leads to broad substrate specificity in the two types of catalytic activities it shows: a peroxida
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https://doi.org/10.1007/978-1-4615-0667-6Carcinom; DNA; Oxidation; amphetamine; dopamine; metabolism; neurotoxicity; transcription
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