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Titlebook: Biological Effects of Polynucleotides; Proceedings of the S Roland F. Beers,Werner Braun Conference proceedings 1971 Springer-Verlag New Yo

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Influence of Synthetic Polynucleotides on the Bactericidal Power of Mouse Macrophages Against ,f enhanced host resistance to viral infection. Since then, it has been shown that synthetic double-stranded polynucleotides, such as poly I:C and poly A:U, can increase the resistance of the host against several viral infections and experimental tumors as will be reported in this Symposium.
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Conference proceedings 1971ot only carry and transmit specific infOImation but also can act as less specific triggers of antiviral factors and of immunological responses. The latter properties are of particular interest in terms of possible utilization in human and veterinary medicine and consequently led, in the last few yea
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Qualitative and Quantitative Aspects of Polynucleotide Modificationtructure or conformation of the polymer. As will be discussed later, the reactivity of bases in a polymer with particular reagents can be quite dissimilar to that in a monomer, depending on whether the base is hydrogen bonded in a double-stranded structure, whether there are stacking interactions, o
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