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Titlebook: Biological Basis of Oncologic Thermotherapy; Michel Gautherie Book 1990 Springer-Verlag Berlin Heidelberg 1990 Tumor.cancer.cancer treatme

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期刊全称Biological Basis of Oncologic Thermotherapy
影响因子2023Michel Gautherie
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学科分类Clinical Thermology
图书封面Titlebook: Biological Basis of Oncologic Thermotherapy;  Michel Gautherie Book 1990 Springer-Verlag Berlin Heidelberg 1990 Tumor.cancer.cancer treatme
影响因子Studies on the effects of hyperthermia have aroused great interest in recent years. On the one hand, it has been demonstrated. that hyperthermia may be a useful treatment modality for tumors, in combination with ionizing radia­ tion or cytotoxic drugs. On the other hand, it is of great scientific interest to study the effects of increased temperature on biological systems. Although hyperthermia has been used in the treatment of cancer for cen­ turies, its therapeutic success was doubtful. However, since it has been shown that radiation-induced cell killirtg can be remarkably enhanced by hyperthermia, many investigations have been performed with cells in vitro, tumors in situ, and normal tissues. From these studies it has been concluded that many biological phenomena and their characteristics which are found in tumors may be conducive to the use of hyperthermia in cancer therapy. Many researchers are studying the cell-killing mechanisms of heat and fac­ tors that modify cell thermosensitivity. A very fascinating biological phenomenon is the general observation that living cells can enhance their thermoresistance within hours of heat treatment. The development of such thermotolerance
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Pathophysiological Mechanisms of Hyperthermia in Cancer Therapy, damage in tumors by hyperthermia is believed to be related to properties such as tumor blood flow (XBF), tissue oxygenation, pH distribution, and energy status — factors which generally go hand in hand, and in turn define the cellular microenvironment. Whether or not normal and malignant cells have
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The Heat Shock Response: Events Before, During, and After Gene Activation,vated by the use of hyperthermia as a method of treating cancer. Researchers working in this area are concerned primarily with one cell function, namely the cells’ abilities to proliferate indefinitely after being exposed to moderate temperatures. Mammalian cells are the primary model system examine
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https://doi.org/10.1007/978-3-642-74939-1Tumor; cancer; cancer treatment; cell; hyperthermia; oncology; radiation; thermotherapy; Radiaton Oncology
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978-3-642-74941-4Springer-Verlag Berlin Heidelberg 1990
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https://doi.org/10.1007/978-3-642-00990-7ovements and refinements of these therapy modalities, it has proved impossible to develop cures for a great number of individual malignancies, and frequently this is even true of reasonable palliative treatment. Moreover, cancers can frequently develop a high resistance to ionizing radiation or chem
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Th. J. Vogl,A. Wetter,D. Schneidmüllert way to activate those genes involved in the synthesis of easily identified proteins. The area of interest here is related to the specific genes involved in the process, control of activation, and the nature of the RNAs and the proteins and their specific functions.
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