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Titlebook: Biological Basis of Geriatric Oncology; Lodovico Balducci (Professor of Oncology and Medic Book 2005 Springer-Verlag US 2005 age.aging.can

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Replicative Senescence and Cancer,rch is needed to understand the fate of cells with short telomeres in tissues during aging, to understand the effects on neoplasia of telomere shortening in tissues in vivo, to understand whether telomere shortening results in the accumulation of senescent cells in tissues, and, if so, what effects
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The Influence of Advanced Age on Cancer Occurrence and Growth,ts’. This, of course, because the average age of cancer is in excess of 65 years and the median age of most common adult tumors approaches 70 years. Similarly, scientists studying the mechanisms of cancer development and growth are uncovering and elucidating some of the basic molecular and cellular
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Clinical and Biochemical Evaluation Changes Over Aging,nt to understand the complexity of problems that influence health and well being in older persons. This concept was recognized long ago by geriatricians and implemented in the paradigm of “Comprehensive Geriatric Assessment”. Accordingly, many researchers and clinicians have proposed that the direct
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Biological Screening and Impact in Elderly Cancer Patients,lem such as malnutrition or organ malfunction. The question concerning assessment of frailty or future disability remains unsolved and further research is needed. Simple assessments of clinical diagnosis or biochemical markers or a combination of both are probably more suitable. However screening te
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Biological Basis of the Association of Cancer and Aging Comorbidity,be attached to groups of syndromes with common pathophysiological mechanisms. In addition to paying attention to the impact of cancer treatment on comorbidity, or on the impact of comorbidity on the ability to deliver cancer treatment, we will have in the future to pay attention on the direct impact
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