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Titlebook: Bioinformatics of Human Proteomics; Xiangdong Wang Book 2013 Springer Science+Business Media Dordrecht 2013 clinical bioinformatics.mass s

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楼主: CULT
发表于 2025-3-30 09:31:59 | 显示全部楼层
Clinical Bioinformatics in Human Proteomics Research,proteome-based analysis is a promising tool for the identification of prognostic and diagnostic markers as well as for novel therapeutic targets which could be used for the treatment of diseases. The integration of proteome-based approaches with data from genomic or genetic profiling will lead to a
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Proteomics Defines Protein Interaction Network of Signaling Pathways,to probe dynamic PPI dependent on protein posttranslational modifications, which is common for signal transduction. AP-MS mapping protein interaction network of various signal pathways has dramatically increased in recent years. Here, I’ll present the strategies toward obtaining an interactome map o
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Protein Function Microarrays: Design, Use and Bioinformatic Analysis in Cancer Biomarker Discovery otein microarray data. We exemplify this overall approach by reference to the creation of a multiplexed cancer-antigen microarray that contains 100 unique, purified, immobilised antigens in a spatially defined array, and we describe specific methods for serological assay and data analysis on such mi
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Toward Development of Novel Peptide-Based Cancer Therapeutics: Computational Design and Experimentatudy, we present and discuss three novel bioactive peptide ­analogues, designed using the Resonant Recognition Model (RRM), and discuss their biological effects on normal and tumor cells from mouse and human origins.
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Processing of Mass Spectrometry Data in Clinical Applications,ing the integration of experimental data with network datasets, as valuable instrument for identifying alterations that underline the emergence of specific phenotypes. Based on our experience, we show some examples taking into consideration experimental data obtained by multidimensional protein iden
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Proteomic Approaches for Urine Biomarker Discovery in Bladder Cancer,28, identified by proteomic approaches and confirmed by ELISA, showed significant differences compared with normal individuals. The upregulation of urinary ADAM28 in bladder cancer was revealed, so it may be a biomarker of bladder cancer.
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