Titlebook: Bioinformatics in MicroRNA Research; Jingshan Huang,Glen M. Borchert,Bin Wu Book 2017 Springer Science+Business Media LLC 2017 miRNA targe

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Genomic Regulation of MicroRNA Expression in Disease Development,s of other genes, including those encoding transcription factors. On the other hand, the spatial and temporal patterns of miRNAs transcription are subject to regulation by transcription factors. The inter-regulation between miRNAs and TFs integrates two gene regulatory networks—at transcriptional le

怒目而视

Next-Generation Sequencing for MicroRNA Expression Profile,om the NGS methods to the third-generation sequencing methods, we can see the development thread of the sequencing technology. Currently, NGS is the main contender in the sequencing market. NGS technologies provide an opportunity to research the microRNA (miRNA) expression profiles in detail. The NG

DEFT

Handling High-Dimension (High-Feature) MicroRNA Data,uence, the curse of high dimension often becomes a problem. High-dimension variables lead to many difficulties in processing and can be hard to understand. On the other aspect, as the sample size rather limited, the more variables, the more statistical error would be produced in the data processing.

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Involvement of MicroRNAs in Diabetes and Its Complications,action. Both genetic and environmental factors contribute to the development of type 1 and type 2 diabetes. The pathogenesis of diabetes is complex and the underlying molecular mechanisms are only partially understood. MicroRNAs (miRNAs) play a fundamental role in diabetes and its complications. Thi

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Expression of MicroRNAs in Thyroid Carcinoma,l over cellular processes, including development, signaling, metabolism, and apoptosis. A broad range of miRNA are shown to have abnormal expressions in thyroid cancers which could explain the pathology of tumor oncogenesis and disease progression. A review is conducted of the current research on mi

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