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Titlebook: Bioinformatics for Diagnosis, Prognosis and Treatment of Complex Diseases; Bairong Shen Book 2013 Springer Science+Business Media Dordrech

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Identifying Driver Mutations in Cancerentifying driver mutations. We summarize existing methods into several major categories and discuss challenges in discovering the whole spectrum of driver mutations in cancer for future computational and systems biology studies.
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Systems Biology Studies of Gene Network and Cell Signaling Pathway in Cancer Research studies are provided to illustrate the usage of these approaches for developing genetic regulatory networks and cell signaling pathways using microarray and proteomics datasets, respectively. A future outlook of this research field is also discussed.
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Die Gestaltung einer Key-Account-Strategie,erfaces have a uneven distribution of binding free energy. In the . and ., we explain why protein interfaces are complicated and how the current studies deal with this difficult problem. In ., we present an overview on methods to model and predict binding free energy of protein interactions. . concludes this survey with a summary.
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Molecular Diagnostic Techniquesclues as to how to manage the disease more efficiently. A selection of techniques that are currently available to describe a detailed molecular characterization of various cancers is summarized in this volume.
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