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Titlebook: Bioinformatics and Drug Discovery; Richard S. Larson Book 2012Latest edition Springer Science+Business Media New York 2012 cheminformatics

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发表于 2025-3-21 18:50:46 | 显示全部楼层 |阅读模式
期刊全称Bioinformatics and Drug Discovery
影响因子2023Richard S. Larson
视频video
发行地址Contains fully updated protocols on the cutting-edge of the field‘s progress.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from experts
学科分类Methods in Molecular Biology
图书封面Titlebook: Bioinformatics and Drug Discovery;  Richard S. Larson Book 2012Latest edition Springer Science+Business Media New York 2012 cheminformatics
影响因子.Recent advances in drug discovery have been rapid.  The second edition of . Bioinformatics and Drug Discovery .has. .been completely updated to include topics that range from new technologies in target identification, genomic analysis, cheminformatics, protein analysis, and network or pathway analysis. Each chapter provides an extended introduction that describes the theory and application of the technology. In the second part of each chapter,  detailed procedures related to the use of these technologies and software have been incorporated. Written in the highly successful .Methods in Molecular Biology.™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. .Thorough and intuitive,. Bioinformatics and Drug Discovery, Second Edition . seeks to aid scientists in the further study of the rapidly expanding field of drug discovery..
Pindex Book 2012Latest edition
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Functional Characterization of Human Genes from Exon Expression and RNA Interference Results,involved genes and proteins are crucial for modeling and understanding such systems. To interrogate the various cellular processes, high-throughput techniques such as the Affymetrix Exon Array or RNA interference (RNAi) screens are powerful experimental approaches for functional genomics. However, t
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,Barcode Sequencing for Understanding Drug–Gene Interactions, describe in detail a protocol for Barcode analysis by sequencing (Bar-seq) to assess pooled competitive growth of individually barcoded yeast deletion mutants. This protocol has been optimized on two sequencing platforms: Illumina’s Genome Analyzer IIx/HiSeq2000 and Life Technologies SOLiD3/5500. I
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High-Throughput Sequencing of the Methylome Using Two-Base Encoding,ells. Changes in the methylation patterns have been shown to be associated with the development of cancer, growth, neurodevelopmental, and endocrine disorders (Laird PW, Nat Rev Genet 11:191–203, 2010; Tost J, Mol Biotechnol 44:71–81, 2010; Zuo T et al., Epigenomics 1:331–345, 2009). Thus, studying
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Mapping Between Databases of Compounds and Protein Targets,They join the expanding universes of cheminformatics via chemical structures on the one hand and bioinformatics via sequences on the other. However, it is difficult to assess the relative utility of databases without the explicit comparison of content. We have exemplified an approach to this by comp
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