Titlebook: Bioinformatics and Biomedical Engineering; 10th International W Ignacio Rojas,Olga Valenzuela,Francisco Ortuño Conference proceedings 2023

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Structural Analysis of RNA-Binding Protein EWSR1 Involved in Ewing’s Sarcoma Through Domain Assemblys considered as good therapeutic target for treatment of Ewing’s sarcoma. In current study, comparative modeling approach was employed to predict the structural models of three different domains of EWSR1 and Domain Enhanced MOdeling (DEMO) server was used to compose the predicted models of three dom

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Pharmacoinformatic Analysis of Drug Leads for Alzheimer’s Disease from FDA-Approved Dataset Through have been developed to assess therapeutic effects of known drugs against other diseases. In this study, computational drug repositioning method is used to explore the alternative therapeutic effects of FDA approved drugs to treat Alzheimer’s disease. The chemical shape-based screening was employed

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Sven Braun,Christiane Stenger,Jonas Ritterlar docking, and molecular dynamics simulation studies. The best lead drugs, such as darifenacin, astemizole, tubocurarine, elacridar, sertindole and tariquidar displayed promising repositioned effects in the treatment of Alzheimer’s disease and may be used aspotential medicines after thorough experimental and clinical studies.

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