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Titlebook: Bioinformatics Techniques for Drug Discovery; Applications for Com Aman Chandra Kaushik,Ajay Kumar,Shakti Sahi Book 2018 The Author(s) 2018

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发表于 2025-3-21 17:46:04 | 显示全部楼层 |阅读模式
期刊全称Bioinformatics Techniques for Drug Discovery
期刊简称Applications for Com
影响因子2023Aman Chandra Kaushik,Ajay Kumar,Shakti Sahi
视频video
发行地址Reviews new trends in drug discovery.Describes the application of computer science techniques to medical data.Discusses the use of health informatics in the development of new lead compounds?
学科分类SpringerBriefs in Computer Science
图书封面Titlebook: Bioinformatics Techniques for Drug Discovery; Applications for Com Aman Chandra Kaushik,Ajay Kumar,Shakti Sahi Book 2018 The Author(s) 2018
影响因子.The application of bioinformatics approaches in drug design involves an interdisciplinary array of sophisticated techniques and software tools to elucidate hidden or complex biological data. This work reviews the latest bioinformatics approaches used for drug discovery. The text covers ligand-based and structure-based approaches for computer-aided drug design, 3D pharmacophore modeling, molecular dynamics simulation, the thermodynamics of ligand−receptor and ligand−enzyme association, thermodynamic characterization and optimization, and techniques for computational genomics and proteomics..
Pindex Book 2018
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发表于 2025-3-21 20:39:40 | 显示全部楼层
,Structure-Based Approach for In-silico Drug Designing,-aided drug design (SB-CADD) depends on the ability to determine and analyse the 3D structures of the target of interest. In other words, a prerequisite for the SB-CADD approach can be defined based on molecule’s ability to interrelate with a specific ligand, that can be a chemical species or biomol
发表于 2025-3-22 02:18:13 | 显示全部楼层
Three-Dimensional (3D) Pharmacophore Modelling-Based Drug Designing by Computational Technique,erest. In the past few years, pharmacophore models have been developed with chemical features and are intuitively understandable and broadly employed successfully in computational drug discovery by the researchers. The concert and utility of pharmacophore modelling are demarcated by the two major fa
发表于 2025-3-22 08:04:28 | 显示全部楼层
Molecular Dynamics Simulation Approach to Investigate Dynamic Behaviour of System Through the Appligrams to study the complex biological and chemical systems. Broadly used in modern drug design, molecular docking methods can be used effectively to understand the macromolecular structure-to-function relationships and ligand conformations adopted within the binding sites of macromolecular targets.
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Genomics and Proteomics Using Computational Biology,ification and elucidation of protein coding gene structures remains challenging. Methods are limited to computational predictions and transcript-level experimental evidence; hence translation cannot be verified. Proteomic mass spectrometry is a method that enables sequencing of gene product fragment
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Thermodynamic Cycles and Their Application in Protein Targets,optimization, thermodynamic optimization plots and the enthalpic efficiency index, have now been developed to provide proven utility in design process. Improved throughput in calorimetric methods remains essential for even greater integration of thermodynamics into drug design.
发表于 2025-3-23 05:53:22 | 显示全部楼层
2191-5768 r dynamics simulation, the thermodynamics of ligand−receptor and ligand−enzyme association, thermodynamic characterization and optimization, and techniques for computational genomics and proteomics..978-3-319-75731-5978-3-319-75732-2Series ISSN 2191-5768 Series E-ISSN 2191-5776
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