Titlebook: Bioinformatics; An Introduction Jeremy Ramsden Textbook 20092nd edition Springer-Verlag London 2009 algorithms.bioinformatics.biology.compl

小卷发

Introduction to Part IIThe primary purpose of the next two chapters is to give an overview of living systems, especially directed at the bioinformatician who has previously dealt purely with the computational aspects of the subject.

名字的误用

The Nature of Living ThingsFigure 10.1 shows, in highly compressed and schematic form, the major processes taking place within living beings. The first priority of any living being is simply to survive. In the language of §9.4, the being must maintain its essential variables within the range corresponding to life. In succint form, “to be or not to be—that is the question.”

Obstreperous

The Molecules of LifeTable 11.1 gives some approximate values for the atomic composition of a cell. The atomic composition represents a highly reductionist view, somewhat akin to asserting that the informational content of . is ., where . is the normalized frequency of occurrence of the .th letter of the alphabet.

Hectic

ProteomicsThe proteome is the ensemble of expressed proteins in a cell, and proteomics is the study of that ensemble (i.e., the identification and determination of amounts, locations and interactions of all the proteins). The tasks of proteomics are summarized in Fig. 14.1.

招待

Interactomics: Interactions and Regulatory NetworksIt is clear that the living cell, and . the multicellular organism, comprises a great variety of different components that must somehow be integrated into a functional whole. The framework of this integration is directive correlation (Fig. 9.1) and may often be considered as a problem of regulation.

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Jeremy RamsdenProvides a comprehensive, self-contained introduction to the field of bioinformatics and state-of-the-art research.Second edition offers three additional chapters plus many expanded sections.Brings to

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Computational Biologyhttp://image.papertrans.cn/b/image/187151.jpg

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充足

Probability and likelihoodmally, however (i.e., in the sense used throughout this book), probabilities do not refer to judgments, but to .. These outcomes constitute the “sample space.” For example, attributing a probability of 0.6 to an event means that the event is expected to occur 60 times out of 100. This is the “frequentist” concept of probability, based on ..

Bricklayer

Systems, Networks, and Circuitsex objects composed of many individual molecules (the molecule is probably the most appropriate level of coarse graining for the systems we are dealing with). Since these components are connected together, they constitute a system. The essence of a system is that it cannot be usefully decomposed into its constituent parts.