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Titlebook: Bioinformatic and Statistical Analysis of Microbiome Data; From Raw Sequences t Yinglin Xia,Jun Sun Book 2023 Springer Nature Switzerland A

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https://doi.org/10.1007/978-3-319-12850-4 take account for correlated observations with random effects while considering over-dispersion and zero-inflation. First, it reviews and discusses some general issues of GLMMs in microbiome research. Then, it introduces three GLMMs that model over-dispersed and zero-inflated longitudinal microbiome
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Introduction to R for Microbiome Data,r microbiome data analysis (e.g., phyloseq and microbiome). Next it briefly describes three R packages for analysis of phylogenetics (ape, phytools, and castor). Following that it introduces the BIOM format and the biomformat package and illustrates creating a microbiome dataset for longitudinal data analysis.
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Building Feature Table and Feature Representative Sequences from Raw Reads,ng amplicon sequence variants (ASVs) or sub-OTUs. QIIME 2 has warped the two most widely used denoising packages DADA2 and Deblur to generate ASVs and sub-OTUs with 100% identities to clinical variation. This chapter describes and illustrates their uses to generate ASVs or sub-OTUs. First, it introd
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Assigning Taxonomy, Building Phylogenetic Tree,ysis of microbiome data. Chapter . described and illustrated how to generate feature table and feature data (i.e., representative sequences). This chapter describes and illustrates two more core bioinformatic analyses: assigning taxonomy and building phylogenetic tree.
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