Titlebook: Biogenic Amine Receptors; Leslie L. Iversen,Susan D. Iversen,Solomon H. Snyd Book 1975 Plenum Press, New York 1975 pharmacology.psychophar

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Semigroup ,,-algebras and toric varieties,ively review the literature in this vast field, but to point out what seem to be inconsistencies and discrepancies in current concepts concerning the basic processes involved in neurotransmitter secretion.

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Amine Receptors in CNS. I. Norepinephrine,synapses, their exact cellular location, and their mechanism of action have not been known. This chapter will focus on the methods by which the central receptors for NE may be characterized as to location, function, and pharmacological significance.

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Amine Receptors in CNS. I. Norepinephrine,opharmacological actions has been particularly strong for norepinephrine (NE). Basic research in psychiatry has concentrated on the changes in brain monoamine metabolism produced by psychoactive drugs (see Snyder, 1974) to develop catecholamine theories of mental diseases. In such a psychopharmacolo

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Amine Receptors in CNS. II. Dopamine,inergic nerves may function as a neurotransmitter and, according to classical theories of neurotransmission, exert an effect on a specific dopamine receptor, causing permeability changes in the postsynaptic neuron indicative of either excitation or inhibition. This chapter will attempt to provide ev

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Amine Receptors in CNS. III. 5-Hydroxytryptamine in Brain, the existence of 5-HT receptors merely the fact that a cell responds to 5-HT regardless of dose, route of administration, or region of brain, then the topic becomes a broad one indeed. However, the . significance of 5-HT receptors so defined is rather doubtful if the sites in question are not norma

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Receptor Feedback and Dopamine Turnover in CNS,eurons in the central nervous system (Carlsson, 1959; Hor-nykiewicz, 1964; Andén ., 1964., 1965.). At that time, more than 50 years had elapsed since the chemical synthesis of DA was first described by Mannich and Jacobsohn (1910). Although at an early stage DA was found to exert pharmacological eff