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Titlebook: Bioenergetics of the Cell: Quantitative Aspects; Valdur A. Saks,Renée Ventura-Clapier,Michel Rigoul Book 1998 Springer Science+Business Me

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期刊全称Bioenergetics of the Cell: Quantitative Aspects
影响因子2023Valdur A. Saks,Renée Ventura-Clapier,Michel Rigoul
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学科分类Developments in Molecular and Cellular Biochemistry
图书封面Titlebook: Bioenergetics of the Cell: Quantitative Aspects;  Valdur A. Saks,Renée Ventura-Clapier,Michel Rigoul Book 1998 Springer Science+Business Me
影响因子This volume continues the discussion of the problems of in vivo and in vitro. The recently solved X-ray structure of the mitochondrial creatine kinase and its molecular biology cellular bioenergetics - the tradition we started in 1994 by publication of the focused issue of Molecular and Cellular are analyzed with respect to its molecular physiology and Biochemistry, volume 133/134 and a book ‘Cellular Bio­ functional coupling to the adenine nucleotide translocase, as energetics: role of coupled creatine kinases‘ edited by V. Saks well as its participation, together with the adenylate kinase and R. Ventura-Clapier and published by Kluwer Publishers, system, in intracellular energy transfer. The results of the Dordrecht -Boston. In the present volume, use of quantitative studies of creatine kinase deficient transgenic mice are methods of studies of organized metabolic systems, such as summarized and analyzed by using mathematical models of mathematical modeling and Metabolic Control Analysis, for the compartmentalized energy transfer, thus combining two investigation of the problems of bioenergetics of the cell is powerful new methods of the research. All these results, described tog
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A model of O·2 -generation in the complex III of the electron transport chaintochrome c reduction decreased sharply at the same values of the membrane potential. This explains experimental data that the O·.. generation at State 4 appears to be very much faster than at State 3. A mild uncoupling in State 4 can markedly decrease the Superoxide generation due to a decrease in Δ
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Quantitative analysis of some mechanisms affecting the yield of oxidative phosphorylation: Dependenc actual flux through each of the respiratory chain units at constant protonmotive force in yeast mitochondria, we show that the ATP/O ratio decreases when the flux increases. Moreover, the highest efficiency was obtained when the respiratory rate was low and almost entirely controlled by the electro
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Oxidative phosphorylation in intact hepatocytes: Quantitative characterization of the mechanisms of n to carbohydrate, octanoate metabolism by β-oxidation increases the proportion of electrons supplied at the second coupling site of the respiratory chain. This mimics a redox slipping. Octanoate addition results in an increased respiratory rate and mitochondrial NADH/NAD ratio while protonmotive fo
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Yeast mitochondrial metabolism: From , to , quantitative study involved directly in pyruvate metabolism. When the respiratory rate was lowered as a consequence of a high kinetic control of oxidative activity upstream from the respiratory chain, a similar correlation between the increase in ATP/O and decrease in respiratory rate was observed. So, the intrinsic
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Energetics of swelling in isolated hepatocytes: A comprehensive studyes not affect either matrix volume or energetic parameters. This is not the case in isolated rat liver mitochondria incubated in sucrose hyperosmotic medium. Indeed, in this medium, adenine nucleotide carrier is inhibited as the external osmolarity increases, which lowers the state 3 respiration clo
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Adenylate kinase: Kinetic behavior in intact cells indicates it is integral to multiple cellular proolecules generated/consumed in the basal state there is a progressive, apparently compensatory, shift in phosphotransfer catalysis from the CK to the AK system with increasing muscle contraction or graded chemical inhibition of CK activity. AK and CK appear therefore to provide similar and interrela
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