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Titlebook: Biocombinatorial Approaches for Drug Finding; W. Wohlleben,T. Spellig,B. Müller-Tiemann Conference proceedings 2005 Springer-Verlag Berlin

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期刊全称Biocombinatorial Approaches for Drug Finding
影响因子2023W. Wohlleben,T. Spellig,B. Müller-Tiemann
视频video
学科分类Ernst Schering Foundation Symposium Proceedings
图书封面Titlebook: Biocombinatorial Approaches for Drug Finding;  W. Wohlleben,T. Spellig,B. Müller-Tiemann Conference proceedings 2005 Springer-Verlag Berlin
影响因子.Genome- and proteome-based research is generating a significant increase in the number of available drug targets. Correspondingly there is an increasing need for novel, diverse compounds, particularly based on natural compounds, as screening resource. The purpose of the .Ernst Schering Research Foundation Workshop 51. was to provide a forum for an open exchange on perspectives and limitations of biocombinatorial synthesis and the significance of this technology for future drug discovery in  light of this challenge. Experts from academia and industry provided contributions covering: the significance of natural compounds for state-of-the-art drug discovery; the underlying basic principle for the biosynthesis of highly complex compounds; and the scope and limitations of combinatorial biosynthesis regarding formation, identification, optimisation, isolation and manufacturing of novel biologically active entities..
Pindex Conference proceedings 2005
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https://doi.org/10.1007/978-3-322-81397-8e chemistry, genetics and molecular biology are indispensable. The NRPSs can provide such interesting tools to generate and modify novel products. The recently gained structural and mechanistic information on NRPSs have made this class of multienzymes a powerful native tool box that would help to ac
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Krankenkassen — Zwang oder Segen? these GTs show a remarkable flexibility towards the donor and the acceptor molecules making them most valuable for combinatorial biosynthesis. Future work is expected to focus on learning more about sugar biosynthesis, sugar modification and sugar attachment to support in vivo engineering of novel
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https://doi.org/10.1007/b138552Combinatorial Biosynthesis; Diversity; Nonribosomal peptides; Polyketides; Proteome; drug; drug discovery;
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978-3-642-42189-1Springer-Verlag Berlin Heidelberg 2005
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Biocombinatorial Approaches for Drug Finding978-3-540-27055-3Series ISSN 0947-6075
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