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Titlebook: Biochemistry of Vitamin B6 and PQQ; G. Marino,G. Sannia,F. Bossa Conference proceedings 1994 Birkhäuser Verlag 1994 Alanin.Aspartat.Glycog

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Enzyme-substrate interactions modulating protonation and tautomerization states of the aldimines of ino acid decarboxylase (AADC) to the ketoenamine form was studied. In AspAT and ArAT the aldimines exist as the nonprotonated form. Upon binding of substrate amino acids, the p.. of these aldimines are increased and the aldimines become the protonated, ketoenamine form, which is considered to be fav
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Studies on the mechanism of action of D-amino acid transaminasely present in all bacteria but is absent in mammalian cells. The mechanism of action of several enzyme-activated inhibitors (suicide substrates) of bacterial D-amino acid transaminase is reviewed with the objective of defining an inhibitor that might be a useful antimicrobial agent. Site-directed mu
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