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Titlebook: Biochemistry of S-adenosylmethionine and Related Compounds; Earl Usdin,Ronald T Borchardt,Cyrus R Creveling Book 1982 Palgrave Macmillan,

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Turnover in methyl groups in histonesmolecule of the arginine-rich histone fraction H3 from calf thymus 2 out of 13 and in each H4 molecule 1 out of 11 lysyl residues are methylated. Lys (Me.) and Lys (Me.) have been found in H4, whereas H3 contains in addition Lys (Me.) (Hnilica, 1972).
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Protein carboxymethylation in murine neuroblastoma; Effect of methyltransferase inhibitorsratory have further defined the biological characteristics of MNB (Pons, et al, 1981) and its apparent usefulness in elucidating the mechanism of action and efficacy of potential chemotherapeutic agents.
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Carboxylmethylation of rat pancreatic acinar cell zymogen granule membrane proteinsutralization of negative charges on MAP located on the surface of secretory vesicles may promote their movement toward and contact with the secretory pole of the cell and thereby may represent a preliminary step in the exocytotic pathway.
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Regulation of the level of methylation of a protein involved in bacterial chemotaxiser and Koshland, 1977), and that the methyl group is removed enzymatically to yield methanol (Toews and Adler, 1979). More recently, we have focused on regulation of the demethylation reaction and have found a novel effector of this enzymatic activity, cyclic GMP (cGMP).
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https://doi.org/10.1007/978-3-322-84553-5want to point out that neither of these techniques, except to some extent . starvation of methionine (Alix and Hayes, 1974; Alix ., 1979a) can provide any light into the black box that the basic question constitutes: why are these proteins methylated?
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Die Methoden der Kostenauswertungbacteria has now been established as the biochemical sensory input signal in chemotactic action (Springer .., 1979; Springer and Koshland, 1977). In the case of eukaryotes, methylation is studied in various membrane systems involving secretion/excitation and motility/chemotaxis (Diliberto .., 1976b; Gagnon .., 1979; O’Dea et al., 1978).
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