Titlebook: Biochemistry and Biology of Coronaviruses; V. Meulen,S. Siddell,H. Wege Book 1981 The Editor(s) (if applicable) and The Author(s), under e

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,Introduction — Reflections on Work,Glycosylation of viral glycoproteins as a co- and posttranslational event has been studied in a large number of viral systems (for review see Klenk and Rott, 1980). From these data a general picture can be drawn:

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Relatedness of Virion and Intracellular Proteins of the Murine Coronaviruses JHM and A59oteins of coronaviruses have been studied extensively (reviewed in Robb and Bond, 1979). However, little attention has been focused on the intracellular proteins (Bond et al. 1979, Anderson et al. 1979, Siddel et al. 1980).

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Polypeptide Structure of Bovine Enteritic Coronavirus: Comparison between a Wild Strain Purified frohe variability in the data can be accounted for by the different methods used in purification of the virions, protein dissociation and detection on polyacrylamide gel. Furthermore the origin of the virus from animal or from cell cultures can possibly play a role in the difference observed for the same virus.

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Murine Coronavirus RNAextensively studied in recent years (Lomneczi and Kennedy, 1977; Yogo et al., 1977; Lai and Stohlman, 1978; Wege et al., 1978; Macnaughton and Madge, 1978; Guy and Brian, 1979). These studies have shown that the coronavirus genome is a large, single stranded RNA which is polyadenylated and of positive polarity.

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Is there a Supreme Emergency Exemption?es of man and animals.. At least four members of the group are human respiratory pathogens. Others have been suggested to be involved in neurologic and enteric disease processes in man, although none of these strains have yet been isolated in the true sense of the word.. Respiratory strain B814 was