Titlebook: Biochemical Roles of Eukaryotic Cell Surface Macromolecules; 2011 ISCSM Proceedin Perumana R. Sudhakaran,Avadhesha Surolia Conference proce

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CEDE

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ISCSM2011 Chondroitin Sulfate E-type Structure at Tumor Cell Surface Is Involved in Experimental Meeviously, we demonstrated that a Lewis lung carcinoma (LLC)-derived tumor cell line with high metastatic potential showed a higher proportion of E-disaccharide units, GlcUA-GalNAc(4, 6-.-disulfate), in CS chains than low metastatic LLC cells, and that such CS chains are involved in the metastatic pr

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Identification of Endothelial Cell Surface Carbohydrate-Binding Receptors by Carbohydrate Ligand Mi. To investigate the mechanisms underlying cell surface carbohydrate-dependent cancer metastasis, we developed a 7-mer peptide, designated as I-peptide, which is capable of inhibiting FUT3-transfected B16 cell colonization of lung in the mouse. I-peptide inhibited lung colonization of FUT3-B16 cells

GUEER

,Lysosomal Enzyme Sorting Receptors—Where Did They First Appear in the Animal Kingdom?,300 kDa) and the cation-dependent mannose 6-phosphate receptor (MPR46, Mr 46 kDa) are evolutionarily conserved proteins that transport lysosomal enzymes to lysosomes in the vertebrates. MPR300 alone has also been shown to be an endocytic receptor and it also binds human IGF-II. To further understand

staging

Endoplasmic Reticulum-Targeted Bcl-2 Inhibitable Mitochondrial Fragmentation Initiates ER Stress-Inretary proteins, etc. Any functional disturbance in ER triggers programmed cell death if reestablishment of homeostasis is failed. Several studies suggest toward a unique ER-centered apoptotic signaling separate from the Bax and Bak-dependent intrinsic apoptosis signaling during ER stress. Here, we

Ruptured-Disk

Interactions Between Caveolin-1 and Sphingolipids, and Their Functional Relevance,lateral organization of CAV-1 with other molecules within the plasma membrane and the equilibrium between different cellular pools of CAV-1, switching on and off CAV-1- mediated biological events depending on the specific context. The role of sphingolipids in this scenario is very important: sphingo

AMITY

Cell Membrane Repair Pathway Involves Sensing of Dynamics of Caveolae and Caspase-1,binding of H35N, a membrane bound monomer of α-HL, to the host cell arrests the dynamics of caveolae at the cell surface and initiate the membrane repair mechanism involving caspase-1-dependent activation of sterol regulatory element-binding protein-1. Here, we show that the process of membrane repa

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