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Titlebook: Bioassays in Experimental and Preclinical Pharmacology; Karuppusamy Arunachalam,Sreeja Puthanpura Sasidhar Book 2021 The Editor(s) (if app

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发表于 2025-3-21 17:42:33 | 显示全部楼层 |阅读模式
期刊全称Bioassays in Experimental and Preclinical Pharmacology
影响因子2023Karuppusamy Arunachalam,Sreeja Puthanpura Sasidhar
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发行地址Includes detailed protocols that are lab-ready.Features advice from the authors on how best to implement the well-honed techniques.Contains both in vitro and in vivo protocols for full coverage of the
学科分类Springer Protocols Handbooks
图书封面Titlebook: Bioassays in Experimental and Preclinical Pharmacology;  Karuppusamy Arunachalam,Sreeja Puthanpura Sasidhar Book 2021 The Editor(s) (if app
影响因子This detailed book explores protocols for a wide array of preclinical pharmacology and toxicology evaluations to be applied to chemical drugs and their development through .in vitro., involving tissues and cell lines, and in vivo models, using animals as experimental systems, utilized to conduct pharmacological research. Written for the .Springer Protocols Handbooks. series, the methodologies included in this collection have been standardized by the authors through extensive use in the lab so that they are ready to be applied in the labs of readers around the world. .Authoritative and practical, .Bioassays in Experimental and Preclinical Pharmacology. aims to assist undergraduate and postgraduate students, research scholars, scientists, and other academicians performing research in the vital field of drug discovery..
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Phytochemical Analysis,s and hence various levels of research are concentrated on it. This chapter deals with the quantitative and qualitative analyses of different metabolites like total phenolics, flavonoids, saponins, tannins and phytosterols. In detail, the Folin-Ciocalteu colourimetric assay to analyse the total phen
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Preclinical Drug Dose Calculation,art in drug research, is significant as it varies among species. Hence the pharmacokinetics and pharmacodynamics need to consider on dose fixation and various methods are available for this, few of which are described in this chapter. The conversion based on normalization of dose-to-body surface are
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Toxicology Studies: In Vitro and In Vivo,l lines with the measurement of cell damage and an in vivo studies comprising acute and sub-acute toxicity steps using animals are well described in this chapter with detailed formulas and tables. Alamar Blue method, micronucleus and comet tests evaluating the chromosome/DNA level damage and analysi
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Animal Experiments on the Cardiovascular System,sk factors, while its treatment relies on reducing the risk factors like lowering bad cholesterol and reducing blood pressure (BP). This chapter deals with the various protocols related to the risk factors of cardiovascular disease that include the procedures like obtaining electrocardiogram (ECG) a
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Experiments of Antifungal Activities,tory concentration (MIC) and the minimum fungicidal concentration (MFC) are determined by the broth microdilution techniques while the synergistic antimicrobial activity of the tested complexes combined with two antifungal drugs (ketoconazole and amphotericin B) made by checkerboard and biofilm assa
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