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Titlebook: Bioactive Lipids in Health and Disease; Andres Trostchansky,Homero Rubbo Book 2019 Springer Nature Switzerland AG 2019 Arachidonic acid.in

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发表于 2025-3-21 18:21:44 | 显示全部楼层 |阅读模式
期刊全称Bioactive Lipids in Health and Disease
影响因子2023Andres Trostchansky,Homero Rubbo
视频video
发行地址Lipidomic analysis of key metabolic processes.Novel lipid- based therapeutic proposal for neurodegenerative diseases.12 chapters and almost 50 color figures and tables
学科分类Advances in Experimental Medicine and Biology
图书封面Titlebook: Bioactive Lipids in Health and Disease;  Andres Trostchansky,Homero Rubbo Book 2019 Springer Nature Switzerland AG 2019 Arachidonic acid.in
影响因子.The purpose of this book is to introduce the readers on the perspective of the role that unsaturated fatty acids and complex lipids play on health and disease. Bioactive lipids can be modified affecting membrane composition, structure and fluidity in addition to changes in cell signaling associated to lipid-protein (membrane receptors) interactions, issues that are addressed by the authors. This book analyzes key topics involving bioactive lipids and their role in normal signaling and the mechanisms of disease. The book navigates from structural studies of oxidized and non-oxidized lipids to the reactions and cell signaling processes that bioactive lipids play in cardiovascular and neurodegenerative diseases. The book contains the recent advances reported in the literature about lipidomics as well as the role that lipid-derived compounds exert on unfolded protein response and lipid metabolism and disease. This book represents a state of the art introduction to lipid metabolism from a biochemical to an .in vivo. overview being an useful tool for students and investigators. We hope the mechanistic observations on the role of bioactive lipids in health and disease serve a perspective
Pindex Book 2019
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Diffusion and Transport of Reactive Species Across Cell Membranesecule. Some of them, such as nitric oxide and oxygen, are small and hydrophobic and can traverse cellular membranes virtually unhindered. Nitrogen dioxide and hydrogen sulfide find a slightly higher barrier to permeation, but still their diffusion is largely unimpeded by cellular membranes. In contr
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Arachidonic Acid and Nitroarachidonic: Effects on NADPH Oxidase Activityactive oxygen and nitrogen species that results in the production of nitrated derivatives of AA, such as nitroarachidonic acid (NO.-AA). NO.-AA is capable to inhibit NOX2 activity by interfering with p47. migration to the membrane without affecting phosphorylation of cytosolic proteins. Also, NO.-AA
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Dyslipidemia in Ischemia/Reperfusion Injury pre- and post- conditioning, making emphasis mainly on the reduction of oxidative stress. However, few of these efforts have been successfully translated into the clinical setting. The controversial results in regards to the relation between cardioprotective mechanisms and dyslipidemia/hypercholest
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Bioactive Lipids and the Gut-Brain Axis: Diet as a Modulator of Bioactivity and Diversity of Lipids (1) . result from biochemical modification of dietary fatty acids by nutrients and are proposed to play diverse physiological roles, namely by modulating NF-kB and Nfr2-dependent signaling cascades and post-translational modification of proteins. Produced in the gastric compartment, they are absorbe
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Nitroalkylation of α-Synuclein by Nitro-Oleic Acid: Implications for Parkinson’s Disease pleiotropic anti-inflammatory signaling mediators that could interact with α-syn to exert unraveling actions. Herein, we demonstrated that nitro-oleic acid (NO.-OA) nitroalkylate α-syn, forming a covalent adduct at histidine-50. The nitroalkylated-α-syn exhibited strong affinity for phospholipid ve
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