Titlebook: Bio-Nanomedicine for Cancer Therapy; Flavia Fontana,Hélder A. Santos Book 2021 The Editor(s) (if applicable) and The Author(s), under excl

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In Vitro Assays for Nanoparticle—Cancer Cell Interaction Studiesl translation is still scarce. One of the main hurdles contributing for this setback is the lack of reliable in vitro models for preclinical testing capable of predicting the outcomes in an in vivo setting. In fact, the use of 2D monolayers, considered the gold-standard in vitro technique, leads to

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3D Tumor Spheroid Models for In Vitro Therapeutic Screening of Nanoparticless tumor spheroids, are more representing the natural tumor microenvironment. They have been shown to have higher invasiveness and resistance to cytotoxic agents and radiotherapy compared to cells growing in 2D monolayer. Furthermore, to improve the prediction of clinical efficacy of drugs, in the pa

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CRP743

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Viral Nanoparticles: Cancer Vaccines and Immune Modulatorsstem and the tumour microenvironment. Those pathogens have naturally evolved and been evolutionary to specifically infect hosts, replicate, deliver their genome, and spread. These properties, initially considered a disadvantage, have been investigated and edited to turn viruses into precious allies

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