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Titlebook: Bile Acid Biology and its Therapeutic Implications; Proceedings of the F G. Paumgartner,D. Keppler,A. Stiehl Conference proceedings Mar 200

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Feedback regulation of human bile acid synthesistem, in which bile acid synthesis is increased and variation between patients is abolished, we are able to study and find even small effects of individual bile acid on both bile acids synthesis and expression of key enzymes..Both CDCA and DCA significantly decreased the bile acid synthesis, but CDCA
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Mechanisms of bile acid inhibition of bile acid synthesisa SHP-independent and PXR-dependent pathway. PXR inhibition of bile acid synthesis provides a mechanism for protecting the liver from toxicity of bile acids and drugs. This may be the molecular mechanism for using rifampicin and steroids to treat pruritus and cholestasis of the patients with bile ac
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Multifunctional roles of bile acid biosynthetic enzymes and the isolation of a new vitamin D 25-hydr
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Role of CYP3A4 as a cholesterol and bile acid metabolizing enzyme
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Regulation of bile acid biosynthesis by cell signalling pathways
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