Titlebook: Best Practices in Processing and Storage for Hematopoietic Cell Transplantation; Joseph Schwartz,Beth H. Shaz Book 2018 The Editor(s) (if

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Journey of Hematopoietic Cells: Processing to Infusion,used to treat a wide variety of diseases, most commonly leukemias, lymphomas, multiple myeloma, and certain solid tumors. Hematopoietic graft sources include bone marrow, peripheral blood, and cord blood. To maintain a high-quality product to ensure engraftment and optimal patient outcomes, each ste

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Regulations and Accreditation of Processing Laboratories,enters for Medicare and Medicaid Services (CMS) are the main governing bodies that provide federal oversight. State health departments may also have local regulations for processing laboratories. Individuals and institutions involved in cellular therapy processing must be familiar with the requireme

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CD34+ Enrichment and T-Cell Depletionpoietic cell transplantation is rapidly evolving as is our understanding of cellular immunity. Along with this knowledge has come the ability to engineer hematopoietic progenitor cell (HPC) grafts collected from allogeneic donors in the clinical laboratory. Methods including CD34. enrichment and T-c

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Cryopreservation Techniques and Freezing Solutionsither refrigerated or room temperatures for approximately 72 h following collection. Cryopreservation enables long-term storage of HPC products and is used extensively for autologous products collected prior to high-dose chemotherapy (HDT) that are intended for use after treatment to rescue hematopo

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Cord Blood Donor Qualificationnsplantation. The process commences with the recruitment and selection of a suitable donor and finishes with the CB unit (CB) meeting the requirements of pre-release testing parameters, the quality of the product ultimately confirmed by the outcomes observed posttransplant. CB is a biological produc