Titlebook: Behavioral Pharmacology of the Cholinergic System; Mohammed Shoaib,Tanya L. Wallace Book 2020 Springer Nature Switzerland AG 2020 Nicotini

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Endogenous Acetylcholine and Its Modulation of Cortical Microcircuits to Enhance Cognition,ions of in vivo manipulations of endogenous acetylcholine. We find broader similarities than we expected between the cholinergic regulation of sensory and prefrontal cortex, but there are some differences and some gaps in knowledge. In visual, auditory, and somatosensory cortex, the cell and circuit

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Nicotinic Receptors Underlying Nicotine Dependence: Evidence from Transgenic Mouse Models, function are considered. Taken together, these discoveries have provided a foundational understanding of various genetic, neurobiological, and behavioral factors underlying the motivation to use nicotine and related dependence processes, which are thereby advancing drug discovery efforts to promote

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Neuropeptides

,An Evolving Therapeutic Rationale for Targeting the α7 Nicotinic Acetylcholine Receptor in Autism St. Synchronous oscillatory output is an electrophysiological substrate for higher executive functions, such as working memory, and functional connectivity between discrete anatomic areas of the brain. The α. nAChR regulates PV expression and works cooperatively with the co-expressed NMDA receptor in

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Dortmunder Beiträge zur Sozialforschunglcholine receptors (nAChRs). These receptor systems are described in detail within this chapter along with discussion on the successes and failures of synthetic ligands designed to selectively target receptor subtypes for treating brain disorders. New molecular approaches and advances in our underst

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Import Levels of the Developing Countries,hways of the brain. We also discuss the unique roles of homomeric α7 nAChR in behavioral responses to nicotine and how our knowledge of nAChR functional diversity may help guide pharmacotherapeutic approaches for treating nicotine addiction. While nicotine addiction is a truly global problem, the us

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