Titlebook: Behavioral Neurobiology of Depression and Its Treatment; Philip J. Cowen,Trevor Sharp,Jennifer Y. F. Lau Book 2013 The Editor(s) (if appli

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What Can Fear and Reward Learning Teach Us About Depression?,-seeking patients. It is imperative, therefore, to identify novel research strategies to tackle the factors impeding progress. In this chapter we propose that the knowledge derived from computational investigations of associative learning might offer new insights into the neurobiology of MDD.

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New Approaches in the Treatment of Bipolar Depression, illness burden experienced by bipolar patients and is also associated with elevated suicide risk. The treatment of bipolar depression differs from that of recurrent major depression in that the efficacy of conventional antidepressant drugs is not well-established. Some evidence-based treatments for

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Neurosurgical Treatments of Depression,imulation (DBS) via surgically implanted intracerebral electrodes. Although the mechanisms of action of DBS are still not fully understood, preclinical studies are being conducted to elucidate how the treatment might work. DBS in its present form can be considered as a relatively new neurosurgical t

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https://doi.org/10.1007/978-3-8350-9085-9onably reliable. However, classification and diagnosis continue to be based on clinical presentation and course and are not currently informed by aetiological or pathophysiological considerations. It is still unclear, for example, whether or not categories such as melancholic depression represent di

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https://doi.org/10.1007/978-3-8350-9085-9ommonly used as a model of depressive-like behaviour in rodents are described. These tests include those sensitive to antidepressant treatment such as the forced swim test and the tail suspension test, as well as other tests that encompass the wider symptomatology of a depressive episode. A selectio