| 期刊全称 | Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma | | 影响因子2023 | Juan Pedro Martinez-Barbera,Cynthia Lilian Andonia | | 视频video | | | 发行地址 | The first book to target current research on adamantinomatous craniopharyngiomas (ACPs).Topics covered range from pathogenesis to clinical diagnosis to long-term management.Includes novel and effectiv | | 图书封面 |  | | 影响因子 | This astute volume brings together the latest expert research on adamantinomatous craniopharyngiomas (ACPs). ACPs are histologically benign but clinically aggressive tumors exhibiting a high propensity for local invasion into the hypothalamus, optic and vascular structures. These tumors, as well as the current treatments, may result in pan-hypopituitarism, diabetes insipidus, morbid obesity followed by type II diabetes mellitus, blindness, as well as serious behavioral and psychosocial impairments. Exploring in detail advances in both the understanding of tumor biology as well as clinical advances in patient management are explored in detail, this book will also look towards potential new treatment approaches..Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma .is the first book compiling all current research on ACPs. Mouse and human studies have unequivocally demonstrated that mutations in CTNNB1 encoding -catenin underliethe etiology of the majority, if not all ACP tumors. Genetic studies in mice have shown that ACPs are tumors of the pituitary gland and not of the hypothalamus as previously thought, and are derived from Rathke’s pouch precursors. In additi | | Pindex | Book 2017 |
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发表于 2025-3-21 18:20:43
