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Titlebook: Bacterial Therapy of Cancer; Methods and Protocol Robert M Hoffman Book 2016 Springer Science+Business Media New York 2016 bacterial cancer

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发表于 2025-3-21 16:48:31 | 显示全部楼层 |阅读模式
期刊全称Bacterial Therapy of Cancer
期刊简称Methods and Protocol
影响因子2023Robert M Hoffman
视频video
发行地址Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts.Includes supplementary materia
学科分类Methods in Molecular Biology
图书封面Titlebook: Bacterial Therapy of Cancer; Methods and Protocol Robert M Hoffman Book 2016 Springer Science+Business Media New York 2016 bacterial cancer
影响因子.This volumeexplores the evolution of bacterial cancer therapy and describes the moderntechniques used in therapy today. The chapters in this book cover a broad rangeof topics such as the development of tumor-targeting .Salmonella typhimurium .A1-R, a microfluidic device for precise quantification of the interactions betweentumor-targeting bacteria and tumor tissue, non-invasive in vivo imaging ofbacteria-mediated cancer therapy using bio-luminescent bacteria, methods toachieve remote-control of therapeutic gene expression in tumor-targetingbacteria, and cell-cycle decoy of cancer cells resistant to cytotoxic drugs todrug sensitivity by .S. typhimurium .A1-R. This book concludes witha chapter on the future potential of bacterial therapy of cancer. Written inthe highly successful .Methods in Molecular Biology .series format,chapters include introductions to their respective topics, lists of thenecessary materials and reagents, step-by-step, readily reproducible laboratoryprotocols, and tips on troubleshooting and avoiding known pitfalls..Thoroughand informative, .Bacterial Therapy of Cancer: Methods and Protocols .isa valuable resource for anyone who is interested in cancer and bact
Pindex Book 2016
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Oral Delivery of Tumor-Targeting , to Treat Cancer in Mice,een injected intravenously or intraperitoneally into animals or humans. Here, we describe the oral delivery of tumor-targeting . for cancer therapy in a mouse tumor model. We detail the experimental procedures for establishing a mouse tumor model, preparing bacterial culture, mouse gavage, and detec
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Microfluidic Device to Quantify the Behavior of Therapeutic Bacteria in Three-Dimensional Tumor Tismovement and gene expression in tissue is difficult with either monolayers of cells or tumor-bearing mice. Quantification of these interactions is necessary to understand the inherent mechanisms of bacterial targeting and to develop modified organisms with enhanced therapeutic properties. Here we de
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Noninvasive In Vivo Imaging to Follow Bacteria Engaged in Cancer Therapy,ria-mediated cancer therapy using bioluminescent bacteria, it opens up the possibility to follow the course of the microorganisms into the tumor via the circulation. The mechanism by which bacteria elicit their anti-tumor potential is not completely understood. However, this knowledge is crucial to
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Development of a Targeted Gene-Delivery System Using ,,he delivery system is illustrated by targeted delivery of a transgene (i.e., eukaryotic GFP) by . to HER2/.-positive cancer cells. An . strain was engineered with surface display of the anti-HER2/. affibody. To release the gene cargo, a programmed lysis system based on phage ϕX174 gene E was introdu
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Isolation and Analysis of Suppressor Mutations in Tumor-Targeted ,,attenuated in order to provide sufficient safety for administration. Approaches to the generation of attenuated . strains have included deletion of the . gene that is responsible for addition of the terminal myristol group to lipid A. In the absence of myristoylation, lipid A is no longer capable of
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