Titlebook: Bacterial Signal Transduction: Networks and Drug Targets; Ryutaro Utsumi Book 2008 The Editor(s) (if applicable) and The Author(s), under

扫兴

Paleontology

https://doi.org/10.1007/978-0-387-78885-2bacteria; biology; cell; development; drug; drugs; evolution; metabolism; microbiology; pharmaceutical indust

arousal

978-1-4419-2703-3The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines

同义联想法

Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/b/image/180322.jpg

Perigee

Inhibitors Targeting Two-Component Signal Transduction,oped during the past decade and introduce novel drug discovery systems to isolate the inhibitors of the YycG/YycF system, an essential TCS for bacterial growth, in an effort to develop a new class of antibacterial agents.

渐变

Heart-Rate

补助

Eike Marten,Katharina Walgenbachmental change, the signal is transduced from HK to RR through phosphoryl transfer. At the first stage of structural biology of TCS, crystallographic and NMR analyses of domain blocks revealed the folds and the remarkable regions of sensor, dimerization and catalytic domains of HK and receiver and ef

有害

Daniela Schneider,Markus Hilperted at the levels of transcription, translation, proteolysis and protein activity. A key factor in RpoS control is the two-component response regulator RssB, which acts as a direct recognition and targeting factor for ClpXP-mediated RpoS proteolysis. A major, but not the only phosphodonor for RssB is

出来

https://doi.org/10.1007/978-3-658-08594-0el. It has been recently recognized that prokaryotes also regulate many genes and operons at a posttranscriptional level with the participation of small, noncoding RNAs which serve to control translation initiation and stability of target mRNAs, either directly by establishing antisense interactions