Titlebook: Bacterial Biofilms; Tony Romeo Book 2008 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH,

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Physiology of Microbes in Biofilms,ting microbes. Many of the physiological traits that are exhibited in a biofilm environment have been observed and studied previously in detail in planktonic cultures. However, their differential and combinatorial phenotypic expression in distinct subpopulations localized to different regions in a b

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Biofilms on Central Venous Catheters: Is Eradication Possible?, healthcare delivery. Because routine systemic treatment of patients with catheter- associated bloodstream infections is often ineffective, due to the tolerance of biofilm organisms on these devices, other strategies such as the antimicrobial lock treatment (ALT) have been used. This approach involv

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Teresa Marcon,Mike Chiasson,Abhijit Gopalof the treatment. The most effective antimicrobial agents are those (1) that are less affected by the extracellular polymeric substance matrix of the biofilm, (2) that have a more rapid bactericidal effect, or (3) for which the mechanism of action is not dependent upon the growth rates of the organi

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