Titlebook: Bacteria, Complement and the Phagocytic Cell; Felipe C. Cabello,Carla Pruzzo Conference proceedings 1988 Springer-Verlag Berlin Heidelberg

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A New Family of Pore Forming Proteins, the Perforin Family, in Immune Cytolysis by Complement and bsystems is mediated, in part, by pore forming proteins assembling transmembrane tubules on target membranes (for review see 1–5). Perforation of the membrane results in loss of membrane potential, dissipation of transmembrane ionic gradients, Ca-ion entry into target cells, loss of macromolecular ce

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The Molecular Basis of the Interaction of Immunoglobulin G with Complement and Phagocytic Cells, foreign antigenic determinants on the bacterial cell surface. Second, the antibody-coated bacterial cell is recognized by an effector molecule, such as complement C1q or cellular Fc receptor, triggering effector mechanisms, such as complement or phagocytosis, leading to elimination of the bacterial