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Titlebook: BIOACTIVE ANALYTES, Including CNS Drugs, Peptides, and Enantiomers; Eric Reid,Bryan Scales,Ian D. Wilson Book 1986 Springer Science+Busine

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Cyclic Decapeptides in Kidneyfrom these fungi and ascertained to be cyclic polypeptides; they have been shown in laboratory animals to cause nephro-toxicity characteristic of Cortinarius mushroom poisoning. HPLC systems, besides TLC, have been developed to examine methanolic extracts of kidney tissue from poisoned animals for t
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Analysis of Protein Growth Factors and Optimization of Their Separation by HPLChich give high resolution and recovery and preserve biological activity. Resolving power in RP-HPLC depends on the nature of the stationary phase, on the pH and ionic strength of the primary solvent, and on the organic modifier used. Hydrophobic ion-pairing agents, anionic or cationic, can enhance s
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HPLC-EC Measurement of Neuropeptides in Biological Sampleses using an electrochemical (EC) detector coupled with a suitable HPLC system. Peptides are generally measured by immunological procedures (e.g. RIA) which achieve high sensitivities, but can also produce false-positive measurements due to antibody (Ab) cross-reactivity with structurally related pep
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Immunometric Approach to Peptide Hormone Analysisays (e.g. RIA) for peptide hormones, notably in respect of detection limits, specificity, working range, incubation time and ruggedness — as now explored. For ACTE we have developed and selected compatible mouse MAb’s directed towards the near-N-terminal (residues 14–18) and C-terminal (residues 24–
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