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Titlebook: Autophagy in Health and Disease; Potential Therapeuti Kursad Turksen Book 2018 Springer Nature Switzerland AG 2018 Aging.Diabetes.Mitochond

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发表于 2025-3-21 18:22:37 | 显示全部楼层 |阅读模式
期刊全称Autophagy in Health and Disease
期刊简称Potential Therapeuti
影响因子2023Kursad Turksen
视频video
发行地址Explores the applications of autophagy in various human diseases, focusing on therapeutic approaches.Chapters are contributed by leading authorities.Also includes useful discussions of studies derived
学科分类Stem Cell Biology and Regenerative Medicine
图书封面Titlebook: Autophagy in Health and Disease; Potential Therapeuti Kursad Turksen Book 2018 Springer Nature Switzerland AG 2018 Aging.Diabetes.Mitochond
影响因子This timely volume explores the impact of autophagy in various human diseases, emphasizing the cell biological aspects and focusing on therapeutic approaches to these diseases. .The chapters cover autophagy and its potential applications on diseases ranging from obesity, osteoarthritis, pulmonary fibrosis, and inflammation, through ALS, Parkinson‘s, retinal degeneration, breast cancer, alcoholic liver disease and more. The final chapters round out the book with a discussion of autophagy in drug discovery and ‘bench to bedside‘. Chapters are contributed by leading authorities and describe the general concepts of autophagy in health and disease, marrying cell biology and pharmacology and covering: studies derived from preclinical experiments, manufacturing considerations,and regulatory requirements pertaining to drug discovery and manufacturing and production. This volume will be useful for basic scientists as well as already practicing cliniciansand advanced graduate students..
Pindex Book 2018
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发表于 2025-3-21 21:52:11 | 显示全部楼层
Fine-Tuning the Stem Cell Fate by Autophagy,ponents by autophagy is the major pathway for intracellular degradation and recycling. Autophagy plays an important role in maintaining cellular homeostasis and tissue remodeling during normal development. Basal level of autophagy is prevalent in most tissues and it adds to the normal turnover of cy
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Role of Autophagy in Aging of Hematopoietic Stem Cells and Their Niche: Relevance in Clinical Transstic anemia. Efficacy of clinical transplantation critically depends on functionality of the hematopoietic stem cells (HSCs) present in the donor graft, and therefore, it is essential that every precaution should be taken to ensure that the donor HSCs possess good engraftment ability. Aging is known
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Forkhead Box O (FoxO) Transcription Factors in Autophagy, Metabolic Health, and Tissue Homeostasis,bolism. The FoxO–autophagy axis has been shown to mediate cell differentiation and tissue development. Dysregulated FoxO activity may compromise tissue development and homeostasis, concomitant with metabolic abnormalities across tissues such as liver, adipose tissue, skeletal muscle, and heart. In t
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Apoptotic Cell Clearance in Gut Tissue: Role of Intestinal Regeneration,ells drop out in a few days, and regeneration occurs subsequently; cells are eliminated by apoptosis. Clearance of dead cells frequently occurs in the intestinal tract, and apoptotic cells and phagocytes cooperate to facilitate cell clearance quickly and efficiently. The complex signaling network fo
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The Role of Autophagy in Mesenchymal Stem Cell-Based Suppression of Immune Response,herapeutic agents for the treatment of autoimmune, ischemic and degenerative diseases. One of the major barriers for successful transplantation of MSCs is their poor survival after engraftment in the inflamed and hypoxic tissues. Since autophagy regulates survival, differentiation potential, immunom
发表于 2025-3-23 04:31:37 | 显示全部楼层
Emerging Connections: Synaptic Autophagy in Brain Aging and Disease,lles in neurons via macroautophagy opens a new avenue to rejuvenate the protein pools and, thus, promotes synaptic and neuronal integrity and function. Evidence shows that autophagy is crucial in regulating neuronal development and maintaining neuronal integrity. Recent work has demonstrated that au
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Virus and Autophagy: Enemies or Allies, critical times in development and in response to nutrient stress. This process also plays a housekeeping role in removing misfolded or aggregated proteins and clearing damaged organelles. Virus-induced autophagy has a dual role since it may be beneficial to the host by eliminating intracellular pat
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