Titlebook: Autoimmunity and the Pathogenesis of Diabetes; Fredda Ginsberg-Fellner (Professor of Pediatrics, Book 1990 Springer-Verlag New York Inc.

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The Pathogenesis of Immunologically Mediated Diabetes,ideas and theories are hotly debated in the light of experimental data. In this chapter, we approach our subject as immunologists rather than endocrinologists; it is now clear that type I diabetes, both in man and in animal models, is a pathologic process with an immunologic etiology..

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Christian Brockmann,Heinrich Müller demonstration, it has been shown that type I diabetes has a prodromal phase during which islet-cell autoantibodies can be demonstrated in the circulation. and that islet-cell antibodies are an important predictive hallmark of type I diabetes mellitus.

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The Humoral Anti-Islet Immune Response: Immunochemical Studies of Glycoconjugate Antigens, demonstration, it has been shown that type I diabetes has a prodromal phase during which islet-cell autoantibodies can be demonstrated in the circulation. and that islet-cell antibodies are an important predictive hallmark of type I diabetes mellitus.

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https://doi.org/10.1007/978-3-642-34182-3,. and from the finding of genetic linkage between susceptibility to type I diabetes and the HLA loci.. In addition it was discovered almost simultaneously that many type I patients have autoantibodies reactive with the islets of Langerhans,. whereas patients with type II disease were essentially al

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Gesture Modelling for Linguistic Purposesdly destroyed by the diabetogenic process when transplanted into the diabetic twin, and the ability of such immunosuppressive drugs as azothioprine. and cyclosporin A. to preserve beta-cell function and increase remission rates in newly diagnosed, insulin-dependent diabetics, provide the strongest e

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