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Titlebook: Aquaporins; Baoxue Yang Book 2023Latest edition The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Natur

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发表于 2025-3-21 19:01:51 | 显示全部楼层 |阅读模式
期刊全称Aquaporins
影响因子2023Baoxue Yang
视频videohttp://file.papertrans.cn/161/160495/160495.mp4
发行地址Provides a state-of-the-art on recent developments and future directions in aquaporin research.Provides a systematic and comprehensive overview into aquaporins.Covers diverse aspects of aquaporin rese
学科分类Advances in Experimental Medicine and Biology
图书封面Titlebook: Aquaporins;  Baoxue Yang Book 2023Latest edition The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Natur
影响因子.This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. .Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. .By focusing on the advances made over the last 30 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in orde
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发表于 2025-3-21 23:22:32 | 显示全部楼层
https://doi.org/10.1007/978-3-662-35238-0ystallographic methods or cryo-electron microscopy technology show that AQP monomer consists of six membrane-spanning alpha-helices that form the central water-transporting pore. AQP monomers assemble to form tetramers, forming the functional units in the membrane, to transport water or other small
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Die Bausteine mikrofundierter Erklärungenof AQP superfamily, the evolutional relationship has attracted much attention with multiple publications on “the genome-wide identification and phylogenetic analysis” of AQP superfamily. A pair of NPA boxes forming a pore is highly conserved throughout the evolution and renders key residues for the
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https://doi.org/10.1007/978-3-531-92591-2pecially in cerebral ischemia, congestive heart failure, hypertension, and angiogenesis. Therefore, further studies are needed to elucidate the mechanism accounting for the association between AQPs and vascular function-related diseases, which may lead to novel approaches to the prevention and treat
发表于 2025-3-23 05:00:57 | 显示全部楼层
https://doi.org/10.1007/978-3-531-92591-2ucosal gland secretion. In this chapter, we mainly focus on the expression of four AQPs in the lungs, which include AQP1, AQP2, AQP4, and AQP5 in normal and disease status, and the experience of AQPs function from various model and transgenic mice were summarized in detail to improve our understandi
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