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Titlebook: Apoptosis, Senescence and Cancer; David A. Gewirtz,Shawn E. Holt,Steven Grant Book 2007Latest edition Humana Press 2007 Tumor.apoptosis.le

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Elements of Classical Plasticity Theoryunction of DNA-PK is to promote DNA end synapsis and regulate DNA end processing in the nonhomologous end-joining pathway of double-strand break repair. This regulation is mediated in part by DNA-PK-catalyzed phosphorylation of both itself and the Artemis nuclease, which trims heavily damaged ends t
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David A. Gewirtz,Shawn E. Holt,Steven GrantIn-depth discussions of different modes of cell death.Introductory chapters provide detailed overviews of topics
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Cancer Drug Discovery and Developmenthttp://image.papertrans.cn/a/image/159016.jpg
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Numerical Analysis of Bifurcations,iting promise for cancer treatment. This review will discuss the current understanding of the molecular signaling events that originate from extracellular sources to initiate apoptosis, how the pathway is activated by conventional chemotherapeutic agents, and novel opportunities to exploit the extrinsic pathway for cancer treatments.
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