Titlebook: Apoptosis, Cell Signaling, and Human Diseases; Molecular Mechanisms Rakesh Srivastava Book 2007 Humana Press 2007 DNA.HIV.gene expression.g

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The Role of Phosphoinositide 3-Kinase-Akt Signaling in Virus Infectionrease their survival, in addition to other established mechanisms such as expression of viral onco-genes and direct inhibition of proapoptotic proteins. Recent research has revealed that this pathway is up-regulated by a number of viruses during both short-term acute infections and long-term latent

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MAPK Signaling in Human Diseasesological functions of the MAPKs with an emphasis on the regulation of cell survival and proliferation by these enzymes, and will also discuss the development of MAPK pathway inhibitors for the treatment of human diseases.

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Cyclooxygenase-2 Gene Expressione. Many cellular transcription factors bind these elements to regulate the COX-2 gene transcription. Among them, the key factors are NF-kB and b-catenin. Of these, b-catenin is especially interesting because it can egulate COX-2 both directly by binding to the promoter elements as a comples with eit

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Book 2007ws they present systemically examine the most exciting and innovative aspects of their particular areas of expertise. Researchers will find these volumes of major benefit as they search for novel and more effective treatments for human diseases..

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An exact and scientific metaphysics transformed cells typically overexpress uPA and uPAR and show increased activation of the above signaling modules. These signaling intermediaries are involved in the expression of uPA and uPAR as well as mitogenesis, neoplastic growth and metaststic spread and tissue remodeling as occurs in the pathogenesis of neoplasia.

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