| 期刊全称 | Apoptosis in Cardiac Biology | | 影响因子2023 | Heribert Schunkert,G. A. J. Riegger | | 视频video | http://file.papertrans.cn/160/159011/159011.mp4 | | 学科分类 | Basic Science for the Cardiologist | | 图书封面 |  | | 影响因子 | Apoptosis or programmed cell death is increasingly consideredto be a major factor in the development and progression ofcardiovascular disease. In patients with heart failure the activationof apoptosis may result in the loss of irreplaceable cardiac myocytespromoting the clinical course of the syndrome. Moreover, in thecoronary arteries inflammation and apoptosis may weaken criticalstructures of the vessel wall leading to plaque rupture and,subsequently, to myocardial infarction. Given these deleteriousconsequences, it seems almost paradoxical that programmed cell deathis an active process that, if initiated under physiologicalcircumstances, is essential for both coordinated tissue growth ordestruction of malignant cells. ..Apoptosis in Cardiac Biology., written by a team ofinternationally renowned researchers, gives a timely synopsis of basicmechanisms, cellular and structural targets and, finally, clinicalimplications of programmed cell death in the heart. The expert authorsof this volume give concise overviews on general and cell-specificaspects of programmed cell death in cardiac myocytes and fibroblasts,as well as in vascular smooth muscle and endothelial cells.Furthermore, nov | | Pindex | Book 2000 |
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