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Titlebook: Apoptosis and Its Modulation by Drugs; Ross G. Cameron,George Feuer Book 2000 Springer-Verlag Berlin Heidelberg 2000 AIDS.Antigen.Apoptosi

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期刊全称Apoptosis and Its Modulation by Drugs
影响因子2023Ross G. Cameron,George Feuer
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发行地址This book represents the summation of considerable effort from a significant group of contributors from all over the world as well as from its editors..The message contained is well delineated and wil
学科分类Handbook of Experimental Pharmacology
图书封面Titlebook: Apoptosis and Its Modulation by Drugs;  Ross G. Cameron,George Feuer Book 2000 Springer-Verlag Berlin Heidelberg 2000 AIDS.Antigen.Apoptosi
影响因子Apoptosis is a fascinating concept for the basic scientist. This is not only because of the multifaceted variety of proposed and discovered mechanisms, but because apoptosis represents a fundamental pathway for cell renewal. The study of apoptosis has resulted in an array of discoveries on signal transduc­ tion and downstream effects that have facilitated and advanced many fields in biology, including research on cancer and other diseases. Thus, the apoptotic process can be viewed as the largest effort of the scientific community to understand how cells work and tissues assemble or remodel. The most direct consequence of this accumulated knowledge is a greater understanding of disease and pathological mechanisms. The end result of these efforts will be significant contributions to health and the adoption of new, never anticipated, therapeutic approaches. This book represents the summation of considerable effort from a significant group of contributors from all over the world as well as from its editors. In this fashion, many viewpoints have been collected and SUbjected to thorough academic discussion. The concepts contained in this medically important volume will stimulate and rene
Pindex Book 2000
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Apoptotic Cell Phagocytosis,ptosis is histologically inconspicuous because of the speed and efficiency by which cells undergoing this programmed form of cell death are recognised, ingested and degraded by nearby phagocytes. Where the load of apoptotic cells is small the clearance job can be done by neighbouring cells of the sa
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T Cell Apoptosis and Its Role in Peripheral Tolerance,lfantigens in the thymus, elimination of T cells which are infected with viruses, and homeostasis of T cell populations that have expanded following high dose antigen exposures. In this chapter, we will analyze the mechanisms of apoptosis of peripheral T lymphocytes, discuss the role of T cell apopt
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Apoptosis of Nerve Cells,tion will provide the basis for a rationale drug design strategy to treat acute (e.g., stroke, traumatic brain injury, status epilepticus, perinatal asphyxia) and chronic (e.g., Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis) neurodegenerative disorders
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Reactive Oxygen Species and Apoptosis,en certain ROS and the generation of highly reactive ROS at desired locations, as well as their modulation by antioxidants and a variety of enzymes, warrant a hitherto unexpected degree of efficiency and specificity. ROS are involved in triggering and mediating apoptosis under physiological and path
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Clearance of Apoptotic Lymphocytes by Human Kupffer Cells. Phagocytosis of Apoptotic Cells in the L considered a specialized form of phagocytosis, playing a major role in the general tissue homeostasis in physiological and pathological conditions. Phagocytic recognition of apoptotic cells is less well understood than the death program itself, but an increasing number of recent studies are highlig
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