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Titlebook: Apoptosis and Inflammation; James D. Winkler (Assistant Director) Book 1999 Springer Basel AG 1999 apoptosis.cell.cells.diseases.inflammat

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期刊全称Apoptosis and Inflammation
影响因子2023James D. Winkler (Assistant Director)
视频video
学科分类Progress in Inflammation Research
图书封面Titlebook: Apoptosis and Inflammation;  James D. Winkler (Assistant Director) Book 1999 Springer Basel AG 1999 apoptosis.cell.cells.diseases.inflammat
影响因子Apoptosis is a form of cell death that occurs in a controlled manner and is generally noninflammatory in nature. Apoptosis, or programmed cell death, implies a cell death that is part of a normal physiological process of pruning of unneeded cells. However, many disease conditions utilize apoptosis for pathological ends, resulting in inappropriate cell death and tissue destruction. This book starts with an introduction that reviews the general characteristics of apoptosis, its regulation and its role in physiology and disease. Next, the book focuses on three areas as they relate to inflammatory cells and diseases. The first area consists of chapters on signals for apoptosis important to inflammatory cells, namely growth factors and arachidonic acid metabolism. The next area that the book focuses on are effects at the cellular level, on cell survival versus cell death and signals critical for cell function in both normal and disease states. These topics are covered in chapters on lymphocytes, granulocytes, chondrocytes and keratinocytes. The last area that the book focuses on are events at the level of tissue and disease, looking at the evidence for altered apoptosis and/or apoptotic
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Hematopoietic cells, types have “unbalanced” rates of proliferation and death, such that the death rate is decreased relative to the proliferation rate and expansion of the specific population results. As the expanding cell population reaches the point of meeting the increased demand, the drive for expansion subsides.
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Lupus and lupus-like syndromes,R3), DR4, DRS, Fas ligand 2 (FasL2) have not been studied in SLE. Also, there are signaling pathways for apoptosis including Fas-associated protein with death domain (FADD), tumor necrosis factor receptor-1 associated death domain (TRADD), FADD-like interleukin-113 converting enzyme (FLICE) which ar
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https://doi.org/10.1007/978-3-662-28791-0 also be removed from inflamed sites by undergoing programmed cell death. The aim of this chapter is to draw together studies which have pursued these themes over the last 10 years or so. However, at the risk of disappointing some authors, our approach will be selective rather than exhaustive, in vi
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