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Titlebook: Aplastic Anemia; Pathophysiology and Hermann Heimpel,Edward C. Gordon-Smith,Bernhard Ku Book 1979 Springer-Verlag Berlin Heidelberg 1979 A

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发表于 2025-3-21 19:53:17 | 显示全部楼层 |阅读模式
期刊全称Aplastic Anemia
期刊简称Pathophysiology and
影响因子2023Hermann Heimpel,Edward C. Gordon-Smith,Bernhard Ku
视频video
学科分类Haematology and Blood Transfusion‘ Hämatologie und Bluttransfusion
图书封面Titlebook: Aplastic Anemia; Pathophysiology and  Hermann Heimpel,Edward C. Gordon-Smith,Bernhard Ku Book 1979 Springer-Verlag Berlin Heidelberg 1979 A
影响因子Research on aplastic anaemia has until recently been limited to clinical description, morphology and epidemiology. New methods to culture haemopoietic cells, and advances in our knowledge of proliferation and differentiation in the haemopoietic cell system .opened a new area of scientific interest for this "prototype" of haemopoietic failure. In addition, bone marrow transplantation became not only a clinical method of treatment, but also a source of data useful for the discussion of pathophysiological models of aplastic anaemia. This situation prompted us to arrange an international con­ ference on aplastic anaemia, with particular emphasis on its patho­ physiology and the rationals of the current therapeutic approaches. This conference was held at Schloss Reisensburg from July 20-22, 1978 with the participation of both experimental and clinical scientists active in this field or in related areas of research. The proceedings of the symposion reflect the present knowledge as well as the many new questions which arose from the discussions. The editors are gratefully indebted to the participants of this meeting, to Gerlinde Trogele and all the co-workers of the Uni­ versity of Ulm en
Pindex Book 1979
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发表于 2025-3-21 23:52:11 | 显示全部楼层
Clinical Features of Aplastic Anaemiaisms of aplastic anaemia. It is desirable to understand the pathogenesis of disease, perhaps even more than to know the cause, for from such knowledge may come more rational and perhaps more successful treatment for that disease. We should try in discussion and in formal papers, to maintain an open,
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The Role of Viral Infections in Aplastic Anemia the natural history and treatment of marrow aplasia. However, underlying pathogenetic mechanisms remain obscure. A few patients develop aplastic anemia as part of inherited syndromes. Irradiation and chemotherapy for malignant diseases may produce severe, prolonged, focal or diffuse marrow aplasia.
发表于 2025-3-22 11:57:56 | 显示全部楼层
Aplastic Anemia Terminating in Leukemiacardinal symptom of aplastic anemia, that of bone marrow aplasia, may be constitutional, induced by radiation or cytostatics, by certain drugs, or even due to agranulocytosis; and in some cases its origin may be unknown.
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Independent Requirements for Early and Late Stages of Erythropoiesise [1,2]. Both are dependent on erythropoietin and also on serum for colony formation. For CFU-E, the erythropoietin requirement is in keeping with a similar dependence in the whole animal [1, 3]. Their serum requirement reflects only non-specific needs, namely albumin, transferrin, unsaturated fatty
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CFU-C and Colony Stimulating Activity in Human Aplastic Anemiad as being important in the development of this disorder. Among these are loss of hematopoietic stem cells, inhibition of such cells by the humoral or cellular elements, decreased production of hematopoietic stimuli and alteration of the microenvironmental stroma [2, 17].
发表于 2025-3-23 08:40:43 | 显示全部楼层
Aplastic Anemia Terminating in Leukemiacardinal symptom of aplastic anemia, that of bone marrow aplasia, may be constitutional, induced by radiation or cytostatics, by certain drugs, or even due to agranulocytosis; and in some cases its origin may be unknown.
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