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Titlebook: Anxiolytics; Mike Briley,David Nutt Book 2000 Springer Basel AG 2000 brain.development.drug.drugs.feeling.future.peptides.pharmaceutical.p

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发表于 2025-3-21 18:40:33 | 显示全部楼层 |阅读模式
期刊全称Anxiolytics
影响因子2023Mike Briley,David Nutt
视频video
学科分类Milestones in Drug Therapy
图书封面Titlebook: Anxiolytics;  Mike Briley,David Nutt Book 2000 Springer Basel AG 2000 brain.development.drug.drugs.feeling.future.peptides.pharmaceutical.p
影响因子For over thirty years the benzodiazepines monopolised not only the anxiolytic market but also clinical and animal research in anxiety. Indeed many animal tests developed since the 1960s have been optimised for the benzodiazepines and some programmes have even screened candidates as potential anxiolytics on their benzodiazepine-like side-effects rather than their anxiolytic activity. With the realisation of the drawbacks of the benzodiazepines, namely their potential for tolerance and dependency, there has been a renewed interest in alternative anxiolytics both from existing drugs such as the tricyclic and monoamine oxidase antidepressants and from newer agents such as buspirone. In addition anxiety is no longer considered to be a unique entity but rather an umbrella term for a series of specific anxiety disorders such as panic disorder without or with agoraphobia, generalised anxiety disorder (GAD), specific phobias, social phobias and post-traumatic stress disorder (PTSD). These new clinical categories have opened another dimension in the therapy of anxiety requiring the optimisation of treatments for different syndromes. This book is a critical review of today‘s anxiolytics and t
Pindex Book 2000
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发表于 2025-3-21 20:38:04 | 显示全部楼层
978-3-0348-9581-1Springer Basel AG 2000
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Joachim Richter,Ulrich Gasselingfailed to show antipsychotic efficacy in ten hospitalized schizophrenic inpatients receiving a mean dose of 1,470 mg [.]. On the contrary, a growing appreciation for buspirone’s unexpected anxiolytic, but not antipsychotic properties [., .] ultimately influenced the nature of its prospective develop
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Herbert Niederhausen,Andreas Burkertght be useful in the treatment of anxiety disorders. Meprobamate and the first benzodiazepines were effective in alleviating anxiety, while imipramine given in a single dose often accentuated tension and agitation. During the later part of that decade Klein and Fink [.] observed that inpatients with
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Herbert Niederhausen,Andreas Burkertlts in changes in cerebral function. Monoamine oxidase metabolizes and thus inactivates endogenous pressor amines (like serotonin and noradrenaline) as well as ingested amines absorbed from the gut (like tyramine). The therapeutic effect of MAOIs is supposed to be linked to an inhibition of the degr
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Die Verbreitung des elektrischen Kochens,m and long-term treatment. The efficacy of SSRIs is similar to that of tricyclic antidepressants (TCAs) in patients with major depression, apart from in the subgroup of hospitalised in-patients, where TCAs are marginally, but significantly, more effective [.]. In randomised controlled trials, the to
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,Geräte für die elektrische Haushaltküche,anticonvulsant and muscle relaxant properties and their relative safety, rapidly elevated BZs to the treatment of choice for common and recurrent conditions such as anxiety states, tension and insomnia. However, in recent years, attitudes toward these compounds have greatly changed, and growing awar
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