期刊全称 | Antisense Therapeutics | 影响因子2023 | Sudhir Agrawal | 视频video | | 学科分类 | Methods in Molecular Medicine | 图书封面 |  | 影响因子 | Leading researchers offer an authoritative survey and analysis of the latest findings on the rapid development of antisense oligonucleotides therapeutic and their application in various in vivo model systems. The book‘s high-profile contributors provide timely accounts of their state-of-the-art strategies, discussing such topics as the synthesis and purification of oligonucleotides, their selection for a particular gene target, different methods of administration, and the use of various cell lines and cell culture systems. They also examine questions of cellular uptake, in vitro biological activity, in vivo biological activity, the pharmacology and pharmacokinetics of oligonucleotides, and the application of oligonucleotides to the central nervous system. | Pindex | Book 19961st edition |
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