Titlebook: Antimicrobial Drug Action; David Edwards Textbook 1980Latest edition David Edwards 1980 alkaloids.antibiotics.bacteria.cancer.chemotherapy

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https://doi.org/10.1007/978-3-642-81675-8able ., which is by no means a comprehensive list but emphasises those drugs commonly used clinically (puromycin is an exception). In order to understand the mechanism of action of such drugs the process of protein synthesis will be outlined briefly

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Antibacterial Agents 4. Those Affecting Protein Synthesisable ., which is by no means a comprehensive list but emphasises those drugs commonly used clinically (puromycin is an exception). In order to understand the mechanism of action of such drugs the process of protein synthesis will be outlined briefly

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Principles of Antimicrobial Drug Actionnthetic. The antibiotics form the largest group and these may be defined as substances which, produced by micro-organisms, inhibit the growth of or kill other microorganisms. Even this is not a completely satisfactory definition since some microorganisms produce enzymes which are secreted extracellu

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Mechanisms of Drug Resistancelection of preexisting naturally resistant organisms. The efficient elimination of sensitive strains favours the spread of resistant ones. This process occurred with gonococci within a few years of the introduction of sulphonamides, and with staphylococcus resistant to the action of penicillin.

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Drug Action , — General Principlescomes of paramount importance to administer a drug in ways which enable the drug to reach its target as rapidly as possible. Some drugs have a tendency to accumulate in one particular area or organ and thus may be effective for infections of that organ. An example is rifamide which tends to be trapp

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