Titlebook: Antibody Engineering; Methods and Protocol Damien Nevoltris,Patrick Chames Book 2018Latest edition Springer Science+Business Media, LLC, pa

恳求

书目名称Antibody Engineering影响因子(影响力)




书目名称Antibody Engineering影响因子(影响力)学科排名




书目名称Antibody Engineering网络公开度




书目名称Antibody Engineering网络公开度学科排名




书目名称Antibody Engineering被引频次




书目名称Antibody Engineering被引频次学科排名




书目名称Antibody Engineering年度引用




书目名称Antibody Engineering年度引用学科排名




书目名称Antibody Engineering读者反馈




书目名称Antibody Engineering读者反馈学科排名

国家明智

https://doi.org/10.1007/978-3-662-02149-1gen encounter by somatically mutating their genome sequences. The end result is a series of antibodies that display higher affinities and specificities to specific antigens. This process is called affinity maturation. Recent improvements in computer hardware and modeling algorithms now enable the ra

愤慨点吧

Ordeal

用不完

Einführung in die organische Chemiedescribe a simple protocol to make large and diverse libraries based on a single or a limited number of frameworks. The approach is flexible enough to be used with any antibody format, either single-chain (scFv, VHH) or multi-chain (Fv, Fab, (Fab′)2), and to target in a single step the six complemen

Modicum

序曲

陈腐思想

Einführung in die organische Chemie a tedious multistep process that involves the generation of heavy chain as well as light chain display plasmids in different haploid yeast strains followed by yeast mating. Here, we present a focused one-step Golden Gate cloning approach for the generation of yeast surface display Fab libraries tha

陶醉

Stickstoffhaltige Verbindungen,tic tool development. In many case, the protein of interest, or a relevant portion of this protein such as its extracellular domain, is available as purified protein. In such cases, phage display on purified antigen is an easy and fast way to select antibody fragment able to efficiently bind this an

歌剧等

Einführung in die organische Chemiesystem. Approximately 38% of the entire genome codes for plasma membrane proteins; however the discovery and development of antibody binders to such targets are a technical challenge. Methods to raise binders against such targets by cloning and expressing soluble extracellular regions have been met