Titlebook: Annual Update in Intensive Care and Emergency Medicine 2014; Jean-Louis Vincent Book 2014 The Editor(s) (if applicable) and The Author(s),

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Alexander Y. Nikiforov,Alexander I. ChumakovAmerican Medical Association [1], infectious diseases remain a major cause of morbidity and mortality. Despite this, it is unclear whether fever itself is truly the enemy or whether, in fact, the febrile response represents an important means to help the body fight infection. Furthermore, it is uncl

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Alexander Y. Nikiforov,Alexander I. Chumakov that applies to practically all critically ill patients is a greatly disturbed iron homeostasis. Iron redistribution is one of the key factors contributing to the development of anemia, which is common on the intensive care unit (ICU). Nearly all patients develop anemia during their ICU stay [1, 2]

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Advances in Agricultural Biotechnologyinuous renal replacement therapy (CRRT), antimicrobial dose adaptation during ECMO has been completely neglected for decades [2, 3]. However, ECMO has been shown to enhance the already profound physiologic derangements in critically ill patients, thereby significantly altering drug pharmacokinetics

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B. L. Bayne,R. J. Thompson,J. Widdowsan 5 million adults and accounts for more than 1 million admissions each year in the United States. Pneumonia is the sixth leading cause of death worldwide, and age-adjusted mortality is increasing. Despite effective antibiotic therapy, about 12–36 % patients admitted to the intensive care unit (ICU

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Pandemic Around the World: The New Norm,iO.) in order to maintain an adequate arterial oxygen concentration (PaO.). Despite the ubiquitous use of oxygen therapy in critical care, relatively little is known about the benefits and risks associated with oxygen therapy in adult critical illness and the correct dosing of such therapy in differ

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Residue Reviews/Rückstandsberichtepecific biochemical properties, specific physiologic actions, a range of effective doses, and known adverse effects at high doses. Oxygen is widely available and commonly prescribed and the cost of a single use of O. is low. However, there are few evidence-based data on its use in many clinical cond

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Effectuation als Startup-Entscheidungslogikmost serious life-threatening complications associated with difficult airway access, both in emergency intubation in the critically ill [1–4] and in planned intubations (e. g., scheduled surgery or invasive procedures) [5]. To prevent and limit the incidence of life-threatening complications followi

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