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Titlebook: Animal Models of Neurological Disease, I; Neurodegenerative Di Alan A. Boulton,Glen B. Baker,Roger F. Butterworth Book 1992 Springer Scienc

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,Animal Models of Huntington’s Disease, in the US is approx 50/1,000,000 (.; .). Although HD may occur during the juvenile years (.); the manifestation of the disorder typically occurs in middle life, about 35–45 years of age. From the time of onset, an intractable course of mental deterioration and progressive motor abnormalities begins with death usually occurring within 15 years.
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,Rodent Models of Parkinson’s Disease,on of dopamine (DA) and its metabolites is the main neurochemical change in the disease, although other neurotransmitters such as norepinephrine (NE) and serotonin (5-hydroxy-tryptamine, 5-HT) are also reduced (.; .; .; .).
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Sample Selection and Endogeneity, in the US is approx 50/1,000,000 (.; .). Although HD may occur during the juvenile years (.); the manifestation of the disorder typically occurs in middle life, about 35–45 years of age. From the time of onset, an intractable course of mental deterioration and progressive motor abnormalities begins with death usually occurring within 15 years.
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