Titlebook: Animal Models of Neurodevelopmental Disorders; Jerome Y. Yager Book 2015 Springer Science+Business Media New York 2015 autism spectrum dis

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Bilateral Uterine Artery Ligation (BUAL): Placental Insufficiency Causing Fetal Growth Restriction ment, is vulnerable to a number of disorders later in life, as a consequence of the reduction in oxygen and nutrition during gestation and the resulting fetal growth restriction. These conditions include neurological disabilities such as cerebral palsy (CP), intellectual disability, epilepsy, and me

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孤僻

Preterm Rabbit Model of Glycerol-Induced Intraventricular Hemorrhage,bit pups prematurely by C-section at 29-day gestational age (term = 32 days) and inject intraperitoneal glycerol at 3 h age to induce IVH. About 80 % of glycerol-treated pups develop IVH within 8 h age, which can be detected accurately with head ultrasound. These pups are reared in an infant incubat

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蕨类

Fetal Brain Activity in the Sheep Model with Intrauterine Hypoxia,ic due to placental insufficiency or intermittent cord compression, or acute during labor, may give rise to aberrant development and neurologic sequelae. This chapter reviews the metabolic activities and behavioral states of the brain throughout the late fetal period, and the methods for studying th

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AGGER

The Sheep as a Model of Brain Injury in the Premature Infant, brain during successive periods in development. Recent refinements have resulted in preparations that offer a number of significant advantages to model key aspects of human preterm cerebral injury. We describe a global cerebral ischemia preparation that replicates major features of acute and chroni

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A Newborn Piglet Survival Model of Post-hemorrhagic Ventricular Dilatation (PHVD), to significant motor and cognitive morbidity. Several questions about its pathophysiology remain unanswered and animal models have been useful in identifying relevant risk factors and potential mechanisms. In this chapter, we describe a neonatal piglet model of IVH and PHVD involving the injection