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Titlebook: Animal Models of Depression; George F. Koob,Cindy L. Ehlers,David J. Kupfer (Pr Book 1989 Birkhäuser Boston 1989 behavior.biology.central

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期刊全称Animal Models of Depression
影响因子2023George F. Koob,Cindy L. Ehlers,David J. Kupfer (Pr
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图书封面Titlebook: Animal Models of Depression;  George F. Koob,Cindy L. Ehlers,David J. Kupfer (Pr Book 1989 Birkhäuser Boston 1989 behavior.biology.central
影响因子Animal models represent experimental investigations developed in one species for the purpose of studying phenomena in another species and provide numerous advantages for preclinical research. They allow scientists greater control and isolation of important experimental variables. Animal models are safe, reproducible strategies by which to evaluate and design new pharma­ cological treatment strategies, while also allowing direct central nervous system intervention to alter the course of the aberrant behavior. Animal models have been developed for a number of mental illnesses; in this particular domain, they hold the promise to shed light on the still obscure etiologies of these illnesses and ultimately to facilitate the development and testing of "cures. " Yet, true models of mental illness are difficult to develop, because mental illness may be a uniquely human phenomenon. It was based on these considerations that the MacArthur Foundation Research Network on the Psychobiology of Depression set out to sponsor a conference to review the status, problems, promises, and relevance of animal models to the clinical conditions of affective disorders. The conference was held in September 19
Pindex Book 1989
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Book 1989n these considerations that the MacArthur Foundation Research Network on the Psychobiology of Depression set out to sponsor a conference to review the status, problems, promises, and relevance of animal models to the clinical conditions of affective disorders. The conference was held in September 19
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H. A. Mooney,S. P. Hamburg,J. A. Drakeonale, and advantages of animal models are not understood along with their limitations, there will remain a significant risk of either an uninformed rejection of animal modeling research or, on the other hand, an overacceptance of its direct clinical relevance.
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