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Titlebook: Animal Biomarkers as Pollution Indicators; David Peakall Book 1992 Springer Science+Business Media Dordrecht 1992 Biom.classification.deto

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Studies on genetic material,ssing the damage to DNA by environmental pollutants are specific genotoxic effects, especially the increase of neoplastic disease, rather than effects on the reproductive process. For this reason effects of pollutants on genetic material are considered separately from reproductive effects.
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Thyroid function, retinols, haem and regulatory enzymes,o iodine. The overall regulatory mechanisms involved in thyroid hormone control are shown in Figure 6.1, and an outline of the metabolic pathway of the thyroid hormones is shown in Figure 6.2. In addition to providing T. and T., the thyroid gland is also the source of calcitonin, a polypeptide hormone involved in calcium homeostasis.
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The role of biomarkers in environmental assessment,erally present in the affected community. Classical epidemiology has been reactive rather than proactive. The earliest examples, such as nervous disorders among makers of hats (‘mad as a hatter’) and cancer in chimney sweeps, were cases where an abnormally high incidence of disease was noted and traced back to a specific cause.
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Biomarkers of the nervous system,st important of these is acetylcholinesterase (AChE) on which many studies, from detailed molecular biology to large-scale field studies, have been carried out. While the effects of OPs via Cholinesterase inhibition are transient, there are longer-term neurological effects mediated through the neuro
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Studies on genetic material,ssing the damage to DNA by environmental pollutants are specific genotoxic effects, especially the increase of neoplastic disease, rather than effects on the reproductive process. For this reason effects of pollutants on genetic material are considered separately from reproductive effects.
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Mixed function oxidases,inally evolved to handle naturally occurring toxic compounds, they now play an important role in the detoxification of man-made chemicals. Nebert . (1989) consider that the ancestral cytochrome gene is probably 2000 million years old. The major divergence occurred 800 to 1000 million years ago when
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